Caraka Saṃhitā is the foundational body of knowledge of Ayurveda. Translated as simply “Compendium of Caraka” is an ancient Indian medical text. It comprehensively addresses health, disease and practice of medicine. Roughly 2000 years of age it is still valid as far as health maintenance manual. According to Caraka Samhita, there is no curable disease, which can be treated without Shilajit.
Modern-day science when studying Shilajit confirmed many ancient applications and demonstrated efficacy in vivo (in living organisms) and in vitro (in the lab). The prominent names in Shilajit are the Soviet physician A. Shakirov and the Indian pharmaceutical chemist S. Ghoshal. Much follow-up work was conducted by their followers countless physicians, biologists and chemists.
Shilajit Benefits verified by science.
Antioxidant Properties of Shilajit
Shilajit is a compound with potent antioxidant properties. In an article called: “Antilipid Peroxidative Property of Shilajit” the researchers demonstrated that Shilajit inhibits lipid peroxidation induced by cumene hydroperoxide and ADP/FE**. It also reduced the rate of oxidation of reduced glutathione content and inhibited ongoing lipid peroxidation, induced by these agents immediately after its addition of the incubation system. (Yamini B. Tripathi 1996)
Processed extract of mumie efficiently traps hydroxyl radicals, NO- and SO -radicals and also can regenerate ascorbic acid [Ghosal, 1995]. Mumie is an inhibitor of lipid peroxidation induced by cumene hydroperoxide and ADP/Fe2+ complex in a dose-dependent manner. It decreases the rate of oxidation of reduced glutathione and inhibits ongoing lipid peroxidation, induced by these agents, immediately after its addition to the incubation system. Antiradical properties of mumie extract can be attributed to the presence of dibenzo-a- pyrones and fulvic acid It is assumed that the therapeutic properties of some multicomponent preparations, containing mumie in their composition, are caused by anti radical properties of this humus matter. Mumie activates mitochondrial respiration but suppresses activity of succinate – oxidase and NADH-oxidase in mitochondrion. (Igor Schepetkin 2002)
Genuine mumie has a pronounced antimicrobial activity and on contact will neutralize different pathologic microbe strains such as staphylococci, streptococci, coliform bacteria, enterococci, Proteus. This was established by Dr. A. Shakirov in 1967-1969. Traditionally the substance was used to heal wounds producing pus. (Igor Schepetkin 2002)
Shilajit as a natural treatment for Alcohol withdrawal.
“Evaluation of the Anxiolytic Activity of NR-Anx-C (a poly-herbal formulation) in ethanol withdrawal-induced anxiety behavior in rats. In this study, a Shilajit-based formulation was used to control alcohol withdrawal symptoms in vivo. The study demonstrated that the use of the Shilajit based herbal formulation is comparable in efficacy to the use of a pharmaceutical known as Alprazolam (also known as Xanax). The scientists managed to reduce anxiety in rats resulting from alcohol withdrawal symptoms. (I. Mohan 2001)
It is rather exciting to me that it is naturally possible to support emotional health and stability with Shilajit. The frustrating part is that so far only Pürblack was capable of replicating such results naturally by claiming cumulative effects of alcohol neutralization and emotional resilience. Strange is the fact that if in the study one required several auxiliary herbs to create the effect of effective alcohol withdrawal, the leading Shilajit brand on the market seems to manage replicate the effect simply using Shilajit resin alone.
Natural Anabolic Benefits of Shilajit.
Mineral Pitch is a natural anabolic agent. It was traditionally used by Soviet sports and military to maintain health and increase strength and muscle mass while recuperating well and fast. The anabolic effect includes activation of an anabolic process on cell and molecular levels in different organs and tissues. Research have shown that a mumie extract accelerates the process of protein and nucleic acid synthesis, stimulates energy providing reactions in the liver, and promotes transport of minerals into muscle and bone tissue. (Igor Schepetkin 2002)
Moomie (A.k.a. Shilajit) is a nonspecific immune system stimulator. It proliferates lymphocytes, activates the macrophages. It was shown to accelerate regeneration of the immune system (lymphopoietic erythropoiesis). The resin restored more rapidly the number of lymphocytes and peripheral blood, bone marrow and spleen. (Igor Schepetkin 2002)
Blood sugar in diabetes.
In “Effect of D-400, and Ayurvedic Herbal Formulation on Experimentally Induced Diabetes Mellitus” published in Phytotherapy Research volume 10 (1996). In this study, Shilajit was used as a part of an herbal formulation. Obviously the scientists knew that ancient physicians have consistently used genuine Shilajit to treat diabetes often with herbs added to such formulations. In their study, they induced diabetes in vivo to animals and successfully demonstrated that would application of Shilajit based formulation diabetes can be successfully treated through repair and regeneration of endocrine pancreas. (S. K. Mitra 1996)
In a similar study called “effect of Shilajit on blood glucose and lipid profile in alloxan – induced diabetic rats” scientists so that Shilajit produced a significant reduction in blood glucose levels and also produced beneficial effects on the lipid profile. Even though in this study Shilajit was combined with pharmaceuticals in two doses out of three in each case results on blood sugar were beneficial. (N. A. Trivedi 2004) The study confirmed in a way knowledge accumulated prior by Soviet physicians who did not use Shilajit (Moomiyo in Russian) as a self standing drug in medical therapy, but as a supplement to support efficacy of medical treatments. On the other hand, both studies also validated ancient therapies throughout Asian Shilajit/Moomiyo producing regions where the resin was used to actively control and treat people with diabetes prior to availability of modern-day pharmaceuticals.
Cognition enhancing effect.
Mumie / Shilajit Was traditionally used in Indian medicine to attenuate cerebral functional deficit, including amnesia, in geriatric patients. It was shown that Shilajit promoted learning and memory. (Cho-Rok Jung 2002) (Igor Schepetkin 2002)
In 2001 S. Ghosal with other two scientists published a paper called: “Effects of Shilajit on the development of tolerance to morphine in mice”. The scientists empirically demonstrated that administration of Shilajit on a daily basis inhibits development of tolerance to morphine induced analgesia. Morphine being an opioid is traditionally used to control pain. The downside of morphine use is the development of tolerance to it and constantly requiring higher doses leading to addiction to the compound. In the discussion part of the paper one concluded that Shilajit could have a great potential as a prospective inhibitor of analgesic tolerance to morphine. (P. Tiwari 2001)
Interestingly, most Shilajit on the market except only one brand does not demonstrate this effect. This is exactly why in order to get maximum benefits from your Mineral Pitch it is important to go for the brand that is not all hype, but demonstrates efficacy through unique quality. On the other hand, the problem with multiple brands and merchants offering “Shilajit” or imitations is that most of them will never show the efficacy of the substance originally tested in the lab environments.
Sedation and pain control.
“Glycine- and Gaba-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice” was an in vitro study performed at the Department of Oral Physiology at Chonbuk National University, Korea. The research demonstrated that Shilajit mimics GABA and glycine receptors activation in the brain tissue. It was also suggested that it can be used to control certain types of pain. (Hua Yin 2011)
Human growth hormone and testosterone production naturally.
Moomie (Shilajit) may contribute to stimulation of the human body to produce more of its own growth hormone and testosterone. (Igor Schepetkin 2002)
Antitoxic and anti-radiation.
Mumyo was traditionally used in To detoxify and nourish. In a doctoral dissertation called “Moomiyo effect on tumor growth and creation of blood subjected to x-ray radiation”, a Russian doctor Kaligin V. I. demonstrated the benefits of mineral pitch to counter negative effects of radiation sickness. (Kaligin 1984) Unfortunately, this work is available only in Russian through the central scientific, medical library in Moscow.
Ghosal in 1888 and Bhattacharya in 1989 Demonstrated significant anti-allergic activity of Shilajit stabilizing mast cells and decreasing degranulation. (Igor Schepetkin 2002)
Mineral Pitch (a.k.a. Moomiyo, Mumie, Shilajit, Shilajit) is a traditional anti-inflammatory agent. Greek physicians of antiquity used this medicine for various problems including arthritis and inflammation. (Igor Schepetkin 2002)
The Momie resin is an excellent tool against inflammation. Indeed traditionally it was used in folk medicine to treat people with inflammatory issues. Multiple modern scientific studies demonstrated its efficacy. As an auxiliary, it was conventionally used to support patients with paradentosis, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and cervical spondylosis. Soviet doctors have routinely used it to clean wounds from necrotic tissues, granulation, epithelization, and decrease the period of wound healing. In the lab, Shilajit have demonstrated to be a powerful tool to suppress artificially induced inflammation. (Igor Schepetkin 2002)
“Complement-fixing Activity of Fulvic Acid from Shilajit and Other Natural Sources was published in by an international group of scientists from the Montana State University demonstrated that Shilajit is a highly potent complement fixing agent. Even though the study was performed in vitro it in a way revealed why Shilajit was traditionally used in folk medicine for the treatment of a variety of disorders, including syndromes involving excessive complement activation. The study established that multiple fractions of Shilajit are products of broken down polysaccharides and suggested that such from different plans enhance wound healing and have potential to treat inflammatory disease. (Igor A. Schepetkin 2009)
Moomiyo activates mitochondrial respiration but suppresses activity of succinate – oxidase and NADH-oxidase in Mitochondrion. It induces adults related increase in superoxide dismutase, catalase, and glutathione peroxidase activities as well. This means that while increasing production of energy through a cellular respiration the substance simultaneously protects from damage that usually goes along with increased production of energy. (Igor Schepetkin 2002)
Bones, skin, muscle, organs and other tissue regeneration.
In the article “Medical Drugs From Humus Matter: Focus on Moomie” researchers I. Schepetkin, A. Khlebnikov and Byoung Se Kwon discuss medicinal properties of Moomiyo (also known as Mumie, Shilajit, Salajeet, etc.). According to the article the substance was traditionally used in Asian herbal medicine both inwardly and outwardly against injuries, bone fractures, dislocations, diseases of skin, diseases of peripheral nervous system and also as a soothing and anti-inflammatory agent. (Igor Schepetkin 2002)
In the same article, it is noted that the resin will regenerate damaged bones approximately 2 times faster than they normally would. This effect was used by Soviet surgeons consistently for many years. (Igor Schepetkin 2002)
Moomie showed to be highly effective in the treatment of thermal burns and stimulation of hepatic regeneration. (Igor Schepetkin 2002)
Shilajit is a natural performance enhancer.
Mineral Pitch Resin (Shilajit, Moomiyo, Salajeet, etc.) is a known enhancing cognition. It can protect the neuron tissue in vitro. (Anna Aiello 2008) . As the physical performance enhancer it has been used to promote better strength, recovery, and muscular hypertrophy. (Bucci 2000)
Complete list of citations:
Anna Aiello, Ernesto Fattorusso, Marialuisa Menna, Rocco Vitalone, Heinz C. Schoeder and Werner E.G. Mueller. “Mumiho Traditional Medicine: Fossil Deposits from Antrctica (Chemical.” (eCam) 2008.
Bucci, Luke R. “Selected herbals and human exercise performance.” Edited by American Society for Clinical Nutrition. The American Journal of Clinical Nutrition, 2000: 624-36.
Cho-Rok Jung, Igor A. Shepetkin, Sang B. Wook, Andrei I. Khlebnikov, and Byoung S. Kwon. “Osteoblastic Differentiation of Mesenchymal Stem Cells by Mumie Extract.” Drug Development Research 57 (2002): 122-133.
Ghosal, Shibnath. “Chemistry of shilajit, an immunomodulatory Ayurvedic rasayan.” Pure and Appl. Chem. 62, no. 7 (1990): 1285-1288.
Hua Yin, Eun Ju Yang, Soo Joung Park, and Seong Kyu Han. “Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice.” Korean J Physiol Pharmacol, 2011: 285-289.
I. Mohan, U. S. C. Rao, H. N. Gopalakrishna and V. Nair. “Evaluation of the Anxiolytic Activity on NR-ANX-C (a Polyherbal Formulation) in Ethanol Withdrawal-Induced Anxiety in Rats.” Evidence-Based Complementary and Alternative Medicine (Hindawi Publishing Corporation ), 2001.
Igor A. Schepetkin, Gang Xie, Mark A. Jutila and Mark T. Quinn. “Complement – fixing Activity of Fulvic Acid from Shilajit and Other Natural Sources.” Phytotherapy Research (Wiley InterScience ) 23 (2009): 373-384.
Igor Schepetkin, Andrei Khlebnikov, and Byound Se Kwon. “Medical Drugs From Humus Matter: Focus on Mumie.” Drug Development Research 57 (2002): 140-159.
Kaligin, V. I. “Mumiyo effect on tumor growth and hematopoiesis subjected to x-ray radiation.” Действеие мумие на опухолевый рост и систему кроветворения прирентгеновском облучении. 1984.
N. A. Trivedi, B. Mazumdar, J.D. Bhatt, K. G. Hemavathi. “Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats.” 2004.
P. Tiwari, P. Ramarao and S. Ghosal. “Effect of Shilajit on the Development of Tolerance to Morphine in Mice.” Phytotherapy research 15 (2001): 177-179.
Penpun Wetwitayaklung, Chitima Limmatvapirat and Thaksin Srichan. “Some Biological Activities and Safety of Mineral Pitch.” 2008.
S. K. Mitra, S. Gopumadhavan and T. S. Muralidhar. “Effect of D-400, an Ayurvedic Herbal Formulation on Experimentally Induced Diabetes Mellitus.” Phytotherapy Research 10 (1996).
Suraj P. Agarwal, Rajesh Khanna, Ritesh Karmarkar, Md. Khalid Anwer and Roop K. Khar. “Shilajit: a review.” Phytotherapy Research (Wiley Interscience ) 21 (2007): 401-405.
Talbert, Robert. “Shilajit. A materia medica monograph.” 2004.
Umar, Ahmed R. Al-Himaidi and Mohammed. “Safe Use of Salajeet During the Pregnancy of Female Mice.” Online Journal of Biological Science (Asian Network of Scientific Information) 3, no. 8 (2003).
Williamson, Elizabeth M. “Book Review Shilajit in Perspective.” Narosa, New Delhi, and Alpha Science International, Oxford, UK. Vol. 23. Phytotherapy Research, 2009. 143.
Yamini B. Tripathi, Savita Shukla, Savita Chaurasia and Shashikant Chaturvedi. “Antilipit Peroxidative Property of Shilajit.” Phytotherapy Research 10 (1996): 269-270